Draw the working envelope
Add the machine body, open doors, gantry movement, material feed and room for tool changes. Then mark where the operator stands. A compact product can still demand a wide working zone.
Place support work nearby
Most jobs need a computer, measuring tools, raw stock and somewhere to inspect or finish the part. Give those steps a place before the machine arrives.
Treat dust and fumes as a layout decision
Extraction works best when the route is short, intentional and suitable for the process. Follow the machine manual and applicable workplace rules rather than assuming an enclosure removes the need for control.